Emergence of Klebsiella pneumoniae coproducing KPC-2 and 16S rRNA methylase ArmA in Poland.

نویسندگان

  • Katarzyna Zacharczuk
  • Katarzyna Piekarska
  • Jolanta Szych
  • Elwira Zawidzka
  • Agnieszka Sulikowska
  • Sebastian Wardak
  • Marek Jagielski
  • Rafal Gierczynski
چکیده

A Klebsiella pneumoniae epidemic strain that coproduced carbapenemase KPC-2 (K. pneumoniae carbapenemase 2) and 16S rRNA methylase ArmA has emerged in Poland. Four nonduplicate isolates from patients in a hospital in Warsaw, Poland, were found to carry the bla(KPC-2) and armA genes on ca. 50-kb and 90-kb plasmids, respectively. Tn4401 with a 100-bp deletion in the variable region was detected in all the isolates. XbaI pulsed-field gel electrophoresis (PFGE) revealed 93.2% similarity of the isolates. All the isolates were resistant to carbapenems and 4,6-disubstituted 2-deoxystreptamines.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 55 1  شماره 

صفحات  -

تاریخ انتشار 2011